Search


  • Home
  • Our Research
    • Research
    • Publications
  • How To Participate
    • Goal of the study
    • Who can participate and how?
    • Why by part of our study?
    • Questionnaires
    • Your Report
  • Our Team
    • Scientific Partners
    • Industrial Partners
    • Partner Medical Centers
    • Patient Organization Partners
  • News
  • Contact
  • Home
  • Our Research
    • Research
    • Publications
  • How To Participate
    • Goal of the study
    • Who can participate and how?
    • Why by part of our study?
    • Questionnaires
    • Your Report
  • Our Team
    • Scientific Partners
    • Industrial Partners
    • Partner Medical Centers
    • Patient Organization Partners
  • News
  • Contact

Our Publications

2025

Long X, Wang H, Lu Y, Gao X, Xiao Y, Zhang M, Guo J, Yang J, Zhang R, Li Q, Zhou G, Yang R, Chen F, Wu Q, Sun L, Chu C, Zhu X, Wu Z, Ren Q, You C, Liu Z, Li Q, Liu D, Cheng D, Kang P, Chen A, Wu Q, Fang Q, Wei L, Zhang L Li J, PANAGIOTOU G, Jia W#, Zeng R, Ni Y#, Chen L, Li H# (2025) Interindividual variability in gut microbiome mediates the efficacy of resistant starch on MASLD. Cell Metabolism.
Nikitashina L, Chen X, Radosa L, Li K, Straßburger M, Seelbinder B, Böhnke W, Vielreicher S, Nietzsche S, Heinekamp T, Jacobsen ID, Panagiotou G, Brakhage AA (2025) The murine lung microbiome is disbalanced by the human-pathogenic fungus Aspergillus fumigatus resulting in enrichment of anaerobic bacteria. Cell Rep 44(3), 115442.
Nychas E*, Marfil-Sánchez A*, Chen X, Mirhakkak M, Li H, Jia Q, Xu A, Nielsen HB, Niewdorp M, Loomba R, Ni Y#, Panagiotou G# (2025) Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease. Microbiome 13(1), 10.
Richter KM, Wrage M, Krekeler C, De Oliveira T, Conradi L-C, Menck K#, Bleckmann A# (2025) Model systems to study tumor-microbiome interactions in early-onset colorectal cancer. EMBO Mol Med. 2025 Feb 13. doi: 10.1038/s44321-025-00198-3.
Irmer B, Wlochowitz D, Krekeler C, Richter KM, Chandrabalan S, Bayerlova M, Wolff A, Lenz G, Conradi L-C, Schildhaus H-U, Stadelmann C, Rohde V, Proescholdt M, Salinas G, Homayounfar K, Kuhlmann T, Hailfinger S, Pukrop T, Menck K, Beissbarth T,  Bleckmann A (2025) Consensus molecular subtyping of colorectal carcinoma brain metastases reveals a metabolic signature associated with poor patient survival. Molecular Oncology; 2025 Jan 17. doi: 10.1002/1878-0261.13748.
Byrd DA*, Damerell V*, Gomez Morales MF, Hogue SR, Lin T, Ose J, Shibata D, Toriola AT, Li CI, Figueiredo JC, Stephenson Z, Warby CA, Hardikar S, Siegel EM, Round J, Ulrich CM, Gigic B. The gut microbiome is associated with disease-free survival in stage I-III colorectal cancer patients. (2025) International Journal of Cancer;1‐10. doi:10.1002/ijc.35342.

2024

Hedin KA, Mirhakkak MH, Vaaben TH, Sands C, Pedersen M, Baker A, Vazquez-Uribe R, Schäuble S, Panagiotou G#, Wellejus A#, Sommer MOA# (2024) Saccharomyces boulardii enhances anti-inflammatory effectors and AhR activation via metabolic interactions in probiotic communities. ISME Journal 18(1), wrae212.
Wang Y*, Chen J*, Ni Y, Liu Y, Gao X, Tse MA, Panagiotou G#, Xu A# (2024) Exercise-changed gut mycobiome as a potential contributor to metabolic benefits in diabetes prevention: an integrative multi-omics study Gut Microbes 16(1), 2416928.
Ilozumba MN, Lin T, Hardikar S, Byrd DA, Round JL, Stephens Z, Holowatyj AN, Warby CA, Damerell V, Li CI, Toriola AT, Figueiredo JC, Shibata D, Fillmore GC, Pickron B, Siegel EM, Kahlert C, Florou V, Gigic B#, Ose J#, Ulrich CM#. Fusobacterium nucleatum Abundance is Associated with Cachexia in Colorectal Cancer Patients: The ColoCare Study (2024). Cancer Med, 13: e70431.
Zhou Z*, Kleis L*, Depetris-Chauvin A*, Jaskulski S, Damerell V, Michels KB, Gigic B, Nöthlings U#, Panagiotou G#. Beneficial microbiome and diet interplay in early-onset colorectal cancer. EMBO Mol Med. 2024 Dec 9. doi: 10.1038/s44321-024-00177-0.
Chen, J., Wang, Y., Xu, A., Panagiotou, G. (2024). The Human Gut Mycobiome and Its Potential as a Regulator of the Host’s Metabolic Health. In: Brakhage, A.A., Kniemeyer, O., Zipfel, P.F. (eds) Human and Animal Relationships. The Mycota, vol 6. Springer, Cham. https://doi.org/10.1007/978-3-031-64853-3_6.
Sprague JL, Schille TB, Allert S, Trümper V, Lier A, Großmann P, Priest EL, Tsavou A, Panagiotou G, Naglik JR, Wilson D, Schäuble S, Kasper L#, Hube B# (2024) Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκBmediated barrier protection. Plos Pathogens 20(3), e1012031. DOI: 10.1371/journal.ppat.1012031.
Muli S, Schnermann ME,Merdad M, Rattner J, Achaintre D, Perrar I, Goerdten J, Alexy U, Scalbert A, Schmid M,  Floegel A, Keski-Rahkonen P, Oluwagbemigun K, Nöthlings U. Metabolomics signatures of sweetened beverages and added sugar are related to anthropometric measures of adiposity in young individuals: results from a cohort study. Am J Clin Nutr. 2024 Jul 24:S0002-9165(24)00644-0. doi: 10.1016/j.ajcnut.2024.07.021.
Muli S, Blumenthal A,Conzen CA, Benz ME, Alexy U,Schmid M, Keski-Rahkonen P, Floegel A, Nöthlings U. Associations of ultra-processed foods intake with untargeted metabolomics profiles in adolescents and young adults in the DONALD cohort study. J Nutr. 2024 Sep 25:S0022-3166(24)01040-X. doi: 10.1016/j.tjnut.2024.09.023.
Heilig L, Fariha N, Trinks N, Aimanianda V, Wong SSW, Fontaine T, Terpitz U, Strobel L, Lemauff F, Sheppard D, Schaeuble S, Kurzai O, Hünniger K, Weiss E, Vargas M, Howell PL, Panagiotou G, Wurster S, Einsele H, Löffler J (2024). CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan. PLOS Pathog 20(6), e1012315.
Damerell V, Klaassen-Dekker N, Brezina S, Ose J, Ulvik A, van Roekel EH, Holowatyj AN, Baierl A, Böhm J, Bours MJL, Brenner H, de Wilt JHW, Grady WM, Habermann N, Hoffmeister M, Keski-Rahkonen P, Koole JL, Lin T, Schirmacher P, Schrotz-King P, Ulrich AB, van Duijnhoven FJB, Warby CA, Shibata D, Toriola AT, Figueiredo JC, Siegel EM, Li CI, Gsur A, Kampman E, Schneider M, Ueland PM, Weijenberg MP, Ulrich CM, Kok DE, Gigic B . Circulating tryptophan–kynurenine pathway metabolites are associated with all-cause mortality among patients with stage I–III colorectal cancer. Int J Cancer. 2024; 1‐14. doi:10.1002/ijc.35183.
Schrod S, Zacharias HU, Beißbarth T, Hauschild A-C, Altenbuchinger M (2024). CODEX: COunterfactual Deep learning for the in silico EXploration of cancer cell line perturbations. Bioinformatics, 40, i91-i99. DOI: 10.1093/bioinformatics/btae261.
Görtler F, Mensching-Buhr M, Skaar Ø, Schrod S, Sterr T, Schäfer A, Beißbarth T, Joshi A, Zacharias HU, Grellscheid SN, Altenbuchinger M. (2024). Adaptive digital tissue deconvolution. Bioinformatics, 40, i100-i109. DOI: 10.1093/bioinformatics/btae263.
Oswald LB*, Bloomer A*, Li X, Jean-Baptiste E, Trujillo G, Felder S, Small, BJ, Ose J, Hardikar S, Strehli I, Huang LC, Mooney K, Mutch MG, Chao D, Cohen SA, Karchi M, Wood EH, Damerell V, Loroña NC, Gong J, Toriola AT, Li CI, Shibata D, Schneider M, Gigic B, Figueiredo JC, Jim HSL, Ulrich CM, Siegel EM. Functional quality of life among newly diagnosed young adult colorectal cancer survivors compared to older adults: Results of the ColoCare Study. Support Care Cancer 32, 298 (2024). https://doi.org/10.1007/s00520-024-08511-5.
Berghuijs, K.M.v.T., Kaddas, H.K., Trujillo, G. et al. Age-related differences in employment, insurance, and financial hardship among colorectal cancer patients: a report from the ColoCare Study. J Cancer Surviv 18, 1075–1084 (2024). https://doi.org/10.1007/s11764-023-01362-9.
Holthuijsen DDB, van Roekel EH, Bours MJL, Ueland PM, Breukink SO, Janssen-Heijnen, Keulen ETP, Gigic B, Gsur A, Meyer K, Ose J, Ulvik A, Weijenberg MP, Eussen SJPM. Longitudinal associations of plasma kynurenines and ratios with anxiety and depression scores in colorectal cancer survivors up to 12 months post-treatment. Psychoneuroendocrinology. Volume 163. 2024. DOI: 10.1016/j.psyneuen.2024.106981.
Holthuijsen DDB, EHvan Roekel, Bours MJL, et al. Longitudinal associations of plasma kynurenines and ratios with fatigue and quality of life in colorectal cancer survivors up to 12 months post-treatment. Int J Cancer. 2024; 1-19. DOI:10.1002/ijc.3499.
Garcia-Morena D, Fernandez-Cantos MV, Lopez Escalera S, Lok J, Iannone V, Cancellieri P, Maathuis W, Panagiotou G, Aranzamendi C, El Aidy S, Kolehmainen M, El‑Nezami H, Wellejus A, Kuipers OP (2024). In-vitro influence of specific Bacteroidales strains on gut and liver health related to Metabolic dysfunction-associated fatty liver disease. Probiotics Antimicrob Proteins. 2024 Feb 6. DOI: 10.1007/s12602-024-10219-1.
Peng H, Schmiederer J, Chen X, Panagiotou G, Kries H (2024). Controlling Substrate- and Stereospecificity of Condensation Domains in Nonribosomal Peptide Synthetases. ACS Chem Bio. 2024 Feb 23. DOI: 10.1021/acschembio.3c00678.
Chen J, Lu RS, Diaz-Canestro C, Song E, Jia X, Liu Y, Wang C, Cheung CKY, Panagiotou G#, Xu A# (2024). Distinct changes in serum metabolites and lipid species in the onset and progression of NAFLD in obese Chinese. Comput Struct Biotechnol J 23(2024), 791-800.

2023

Seelbinder B*, Lohinai Z*, Vazquez-Uribe R, Brunke S, Chen X, Mirhakkak M, Lopez-Escalera S, Dome B, Megyesfalvi Z, Berta J, Galffy G, Dulka E, Wellejus A, Weiss GJ, Bauer M, Hube B, Sommer MOA, Panagiotou G. (2023) Candida expansion in the gut of lung cancer patients associates with an ecological signature that supports growth under dysbiotic conditions. Nat Commun 14(1), 2673. DOI: 10.1038/s41467-023-38058-8.
Ose J*, Gigic B*, Brezina S*, et al (2023) Higher Plasma Creatinine Is Associated with an Increased Risk of Death in Patients with Non-Metastatic Rectal but Not Colon Cancer: Results from an International Cohort Consortium. Cancers 2023, 15, 3391.DOI: 10.3390/cancers15133391.
Chen J*, Leal Siliceo S*, Ni Y, Nielsen HB, Xu A, Panagiotou G# (2023). Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions. Microbiome. August 8;11(1):178. DOI: 10.1186/s40168-023-01604-z.
Perrar I, Alexy A, Nöthlings U (2023) Cohort profile update–overview of over 35 years of research in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study. Eur J Nutr. DOI: 10.1007/s00394-023-03290-x.

2022

Himbert C, Warby CA, Gigic B, et al. (2022) Associations of Individual and Combined Physical Activity and Body Mass Index Groups with Proinflammatory Biomarkers among Colorectal Cancer Patients. Cancer Epidemiol Biomarkers; 31 (12): 2148–2156. DOI: 10.1158/1055-9965.EPI-22-0681.
Gigic B, van Roekel E, et al. (2022) Cohort profile: Biomarkers related to folate-dependent one-carbon metabolism in colorectal cancer recurrence and survival – the FOCUS Consortium. BMJ Open;12:e062930.DOI: 10.1136/bmjopen-2022-062930.
*Co-first authors
#Corresponding author